What is social, playful, and more likely to gain weight if it has a particular gene variant? Both people and labradors, apparently.
Researchers in the UK have identified variants, or “versions,” of genes associated with obesity in British Labrador acquisitions. The bad news is that they found variants of the same gene, which also linked to excessive weight loss, in humans. The good news is that both labradors and people with offensive variants can prevent weight lifting by following a strict diet and exercise work, according to Study Published March 6 in the Journal Science.
“Sa pamamagitan ng pag -aaral ng mga aso maaari naming masukat ang kanilang pagnanais para sa pagkain nang hiwalay sa mga may -ari ng control na isinagawa sa diyeta at pag -eehersisyo ng kanilang aso. Sa mga pag -aaral ng tao, mas mahirap pag -aralan kung paano ang genetically driven na gana ay nangangailangan ng higit na lakas na manatiling payat, dahil pareho ang nakakaapekto sa isang tao, “ang nangungunang may -akda na si Eleanor Raffan, isang beterinaryo na surgeon and researcher at the University of Cambridge, told a university statement.
The team measures body fat, defines “lust” levels, and collected saliva samples from 241 labradors. They then compared each dog's body fat to genetic information revealed by saliva samples to determine which genetic substances are likely to be linked to Kanine obesity.
While all dogs have a gene called Dend1B, researchers have found that those with a particular variant of DENND1B – are called RS24430444 – are approximately 8% more body fat than those who do not have it. While researchers also recognized other genes similar to linked to the obesity of the canine, the DennD1b variant had the strongest organization.
“We measure how many dogs have the ones who have their own for food and if they are fussy eaters. Dogs at high genetic risk of obesity [carrying the gene variants linked to obesity] Showing signs of gaining increased appetite, as has also been shown for people with a high risk of obesity of obesity, “explained Natalie Wallis, co-author of the study. Wallis is a researcher in the Department of Physiology, Development, and Neuroscience of the University of Cambridge.
In fact, Wallis and his colleagues announced that Dend1B, along with four other Gens that they wanted to associate with the obesity of the canine, were also indicated in human obesity. Dend1b is involved in the leptin melanocortin path of the brain, a network of neurons that controls the body's energy balance.
Unfortunately, “these Gens do not immediately clearly targets for weight loss drugs, as they control other basic biological processes in the body that should not interfere. -Review.
However, the team also noted that those who have imposed a strict diet regimen and exercise with dogs carrying a variant of DENND1B have been able to prevent obesity with their pets, even though it needs more effort.
“Studying with dogs showed us something really strong: those with slim dogs are not morally superior. The same is true of skinny people. If you have a high risk of obesity genetic, then when many foods available are prone to eating too much and gaining weight unless you put in a great deal of effort,” Raffan said. In other words, people with DennD1B variants linked to obesity are not predetermined to gain weight, but it is more difficult for them to keep it compared to others because of their hypothesized genetic predisposition.
“This work shows how similar dogs are genetically,” he added. “Studying dogs means we have a reason to focus on this particular gene, which led to a major advances in understanding how our own brain controls our behavior and energy use.”
So the next time you advise your lab for supplication, remember that you may have more common than you think!
